Find A Professional
Introduction to Wegovy
Wegovy, known generically as semaglutide, is a medication used for weight management in adults. It functions by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that targets areas of the brain regulating appetite and food intake. This medication is intended for individuals who are obese or overweight with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol.
Common Contraindications
Before starting Wegovy, it's important to consider its contraindications. Individuals with a personal or family history of medullary thyroid carcinoma (MTC) or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use Wegovy. This contraindication is rooted in concerns from rodent studies where semaglutide caused thyroid C-cell tumors. Despite these findings not directly translating to humans, it's a significant precaution for those at potential risk.
Allergic Reactions
Allergic reactions are another critical consideration. Any individual with a known hypersensitivity to semaglutide or any of the inactive ingredients in Wegovy should avoid using the medication. Signs of an allergic reaction can include itching, rash, or severe reactions like difficulty breathing and swelling of the face, lips, or tongue. Immediate medical attention is recommended if any allergic symptoms occur.
Gastrointestinal and Other Conditions
Wegovy may slow gastric emptying and affect medications requiring rapid gastrointestinal absorption. Thus, individuals with severe gastrointestinal disease, including gastroparesis, should use this medication cautiously. Additionally, those with pancreatitis or a history of pancreatitis should discuss their condition with a healthcare provider before starting Wegovy, as there are reports of inflammation developing in patients using GLP-1 receptor agonists.
Pregnancy and Breastfeeding
Wegovy should not be used during pregnancy as weight loss offers no potential benefit and poses risks to the foetus. There's limited data on Wegovy's effects during breastfeeding, but caution is advised as it's uncertain if the drug passes into breast milk. Women who are pregnant, planning to become pregnant, or breastfeeding should consult healthcare professionals before starting this medication.
Drug Interactions
Before beginning treatment with Wegovy, it's essential to review any medications currently being taken with a healthcare provider. This includes both prescription drugs and over-the-counter (OTC) products, particularly medications for diabetes such as insulin or sulfonylureas, to avoid potential hypoglycaemia. Moreover, patients should inform their doctors about any supplements or herbal products they are using, as these can interact with Wegovy.
Conclusion
While Wegovy presents a promising option for weight management, it is crucial to evaluate individual health conditions and any contraindications. Consulting with a healthcare professional is essential to ensure that Wegovy is an appropriate treatment option, maximising its benefits while minimising potential health risks.
Frequently Asked Questions
What are common contraindications for using Wegovy?
Common contraindications include a history of hypersensitivity to semaglutide or any of its components.
Can individuals with a history of pancreatitis use Wegovy?
No, individuals with a history of pancreatitis should avoid using Wegovy.
Is Wegovy safe for people with thyroid cancer risk?
Wegovy is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or in patients with multiple endocrine neoplasia syndrome type 2.
Can pregnant women use Wegovy?
Wegovy is not recommended for use in pregnant women.
Are there contraindications related to breastfeeding?
It’s advisable for breastfeeding women to avoid Wegovy due to potential risks to the infant.
Is Wegovy suitable for individuals with gallbladder disease?
Patients with a history of gallbladder disease should use Wegovy with caution.
Can Wegovy be used in combination with insulin?
Caution is advised if Wegovy is used with insulin or insulin secretagogues due to the risk of hypoglycemia.
Should individuals with severe gastrointestinal disease use Wegovy?
Wegovy is not recommended for people with severe gastrointestinal disease.
Is severe renal impairment a contraindication for Wegovy?
Individuals with severe renal impairment should use Wegovy cautiously or avoid it.
Can individuals with liver disease take Wegovy?
Wegovy should be used with caution in patients with hepatic impairment.
What about the use of Wegovy in patients with eating disorders?
Wegovy should not be used in individuals with active eating disorders.
Are there any medication interactions to be aware of when using Wegovy?
Care should be taken when using Wegovy with other medications that affect blood sugar levels or slow gastric emptying.
Is Wegovy appropriate for adolescents?
Wegovy is not approved for use in individuals under 18 years of age.
What are the considerations for elderly patients taking Wegovy?
Elderly patients may use Wegovy but should be monitored closely for adverse reactions.
Can Wegovy be used in patients with depression?
Patients with depression should use Wegovy cautiously and under medical supervision.
What should patients with Crohn’s disease know about using Wegovy?
Patients with Crohn’s disease should use Wegovy with caution and under the guidance of a healthcare provider.
Is Wegovy contraindicated for patients with history of suicidal thoughts?
It is important for patients with a history of suicidal thoughts to discuss risks with their healthcare provider before using Wegovy.
Can Wegovy be used by individuals with heart disease?
Patients with heart disease should use Wegovy under the care of a healthcare professional.
Are there any genetic conditions that contraindicate the use of Wegovy?
Yes, specifically multiple endocrine neoplasia syndrome type 2 is a contraindication.
What is advised for patients with diabetic retinopathy considering Wegovy?
Patients with diabetic retinopathy should use Wegovy cautiously and have regular eye examinations.
Useful Links
- Ergsy carfully checks the information in the videos we provide here.
- Videos shown by Youtube after a video has completed, have NOT been reviewed by ERGSY.
- To view, click the arrow in centre of video.
- Most of the videos you find here will have subtitles and/or closed captions available.
- You may need to turn these on, and choose your preferred language.
- Go to the video you'd like to watch.
- If closed captions (CC) are available, settings will be visible on the bottom right of the video player.
- To turn on Captions, click settings .
- To turn off Captions, click settings again.